• Jose Luis Bauza Quetglas Urology Department, Son Espases University Hospital
  • Maria Isabel Fullana
  • Javier Asensio
  • Manuel Díaz
  • A.M. Pinheiro
  • Javier Asensio
  • Vasile Cristian Casu
  • Manuel del Rio


A 74 year-old male with a history of high blood pressure and hyperuricemia was admitted to the hospital with asthenia, unquantified weight loss, dyspnea on moderate exertion for 2 weeks, and diffuse abdominal pain. Blood leukocyte count was 12400/uL, creatinine 0.98 mg/dL, CRP 19 mg/dL, and LDH 318 U/L. The chest X-ray showed a right pleural effusion and the pleural fluid was suggestive of an exudate. Thorax and abdominal CT scan revealed a polycystic right kidney with grade IV hydronephrosis and suggested the presence of a nephropleural fistula. The thoracocentesis was repeated and the pleural fluid / serum ratio of creatinine obtained was higher than 1 (1.35 mg/dL), which is a diagnostic criterion for urinothorax. Finally, a retrograde pyelography was carried out, and confirmed the passage of urinary tract fluid into the pleural cavity. A thoracic drainage tube and a nephrostomy through the superior calyx were placed, both draining purulent material. One month later, the control CT shows a right atrophic kidney and a reduction of the size of the fistulous path.

Urinothorax is an infrequent and underdiagnosed pathology, with few cases reported. It is usually presented as a transudative pleural effusion. Currently, no test is available to confirm the diagnosis, although the ratio of serum creatinine/pleural creatinine could suggest the presence of urinothorax. Radiographic imaging is useful to support the diagnosis. Management of a urinothorax requires a multidisciplinary approach with an emphasis on the correction of the underlying urinary tract pathology, and once corrected, this often leads to a rapid resolution of the pleural effusion.

How to Cite
Bauza Quetglas, J. L., Fullana, M. I., Asensio, J., Díaz, M., Pinheiro, A., Asensio, J., Casu, V. C., & del Rio, M. (2019). URINOTHORAX: AN UNUSUAL CAUSE OF MASSIVE PLEURAL EFFUSION. Annals of Mediterranean Surgery, 2(1), 18-19. https://doi.org/10.22307/2603.8706.2019.02.005
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